Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development and the evolvability of human limbs.

Proceedings of the National Academy of Sciences of the United States of America - 23 Feb 2010

Young Nathan M, Wagner Günter P, Hallgrímsson Benedikt

Abstract excerpt

The long legs and short arms of humans are distinctive for a primate, the result of selection acting in opposite directions on each limb at different points in our evolutionary history. This mosaic pattern challenges our understanding of the relationship of development and evolvability because li...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arm
Share to Biological Evolution
Share to Bone Development

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extremities

Share to Genetic Variation

Share to Haplorhini

Share to Hominidae

Source

Open in PubMed Open full text

Identifiers

PMID: 20133636
DOI: 10.1073/pnas.0911856107
PMCID: PMC2840520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20133636-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development and the evolvability of human limbs.PMID 20133636Read ↗

Developmental Constraints Do Not Influence Long-Term Phenotypic Evolution of Marsupial Forelimbs as Revealed by Interspecific Disparity and Integration Patterns.Semantic proximity Read ↗

Patterns of integration and modularity in the primate skeleton: a review.Semantic proximity Read ↗

A highly conserved ontogenetic limb allometry and its evolutionary significance in the adaptive radiation of Anolis lizards.Semantic proximity Read ↗

Morphological integration versus ecological plasticity in the avian pelvic limb skeleton.Semantic proximity Read ↗

Canalization, developmental stability, and morphological integration in primate limbs.Semantic proximity Read ↗

Morphology, evolution, and the whole organism imperative: Why evolutionary questions need multi-trait evolutionary quantitative genetics.Semantic proximity Read ↗

The impact of artificial selection on morphological integration in the appendicular skeleton of domestic horses.Semantic proximity Read ↗

Morphological integration and evolutionary potential of the primate shoulder: Variation among taxa and implications for genetic covariances with the basicranium, pelvis, and armSemantic proximity Read ↗

Anatomical networks reveal the musculoskeletal modularity of the human head.Semantic proximity Read ↗

The macroevolutionary consequences of phenotypic integration: from development to deep time.Semantic proximity Read ↗

What constrains adaptive radiation? Documentation and explanation of under-evolved morphologies in Anolis lizards.Semantic proximity Read ↗

Body-axis organization in tetrapods: a model-system to disentangle the developmental origins of convergent evolution in deep time.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.