Article
Reassortment between swine influenza A viruses increased their adaptation to humans in pandemic H1N1/09.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 May 2010
Furuse Yuki, Suzuki Akira, Oshitani Hitoshi
Abstract excerpt
In April 2009, pandemic H1N1/09 influenza, which originated from swine influenza, appeared in North America, and it has since spread globally among humans. It is important to know how swine influenza A virus broke the host barrier to cause a pandemic. We analyzed 673 strains of human, avian, and swine influenza viruses and assessed the internal genes PB2, PB1, PA, NP, M, and NS. Here we found accumulation of...
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