From nuchal translucency to intracranial translucency: towards the early detection of spina bifida

Abstract excerpt

It is now clear that the vast majority of major fetal abnormalities can be diagnosed prenatally by ultrasound, that most of these abnormalities can be detected in the first trimester of pregnancy and that women want first-trimester rather than later diagnosis. It is also clear that effective diagnosis of fetal abnormalities often necessitates the identification of easily recognizable markers which direct the...

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