Article
Preliminary evidence that estradiol moderates genetic influences on disordered eating attitudes and behaviors during puberty
11 Jan 2010
Abstract excerpt
BACKGROUND: Puberty moderates genetic influences on disordered eating attitudes and behaviors, with little genetic influence before puberty but large (50%) genetic effects during and after puberty. To date, however, nothing is known about the mechanisms that underlie these effects. Estradiol is a particularly promising candidate, as estrogens become elevated at puberty and regulate gene transcription within...
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