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Article

Repeated DNA sequence involved in mutations affecting transport of sucrose into Streptococcus mutans V403 via the phosphoenolpyruvate phosphotransferase system.

Infection and immunity - 1 Apr 1991

Macrina F L, Jones K R, Alpert C A, Chassy B M, Michalek S M

Abstract excerpt

Mutants of Streptococcus mutans V403 defective in the intracellular sucrose-6-phosphate hydrolase (product of the scrB gene) are sensitive to sucrose because of the intracellular accumulation of the phosphorylated sugar. Using a scrB mutant prepared by allelic exchange, we have isolated and chara...

Topics

Animals
Base Sequence
Biological Transport
DNA, Bacterial
Dental Caries
Mutation
Phosphoenolpyruvate Sugar Phosphotransferase System
Rats
Rats, Inbred F344
Repetitive Sequences, Nucleic Acid
Streptococcus mutans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sucrose

Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 2004831
DOI: 10.1128/iai.59.4.1535-1543.1991
PMCID: PMC257873

Genes

PTS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2004831-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Repeated DNA sequence involved in mutations affecting transport of sucrose into Streptococcus mutans V403 via the phosphoenolpyruvate phosphotransferase system.PMID 2004831Read ↗

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