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Article

Role of inflammatory cytokines and eNOS gene polymorphism in pathophysiology of pre-eclampsia.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Mar 2010

Singh Archana, Sharma Deepika, Raghunandan Chitra, Bhattacharjee Jayashree

Abstract excerpt

PROBLEM: Pre-eclampsia involves endothelial vascular dysfunction. The aim of this study was to test the hypothesis that (i) endothelial nitric oxide (NO) synthase Glu298Asp gene polymorphism limits constitutive NO production causing endothelial dysfunction and (ii) inflammatory cytokines impairs endothelium dependent relaxation in pre-eclampsia. METHOD OF STUDY: This cross-sectional study included 50 women with...

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Identifiers

PMID: 20047583
DOI: 10.1111/j.1600-0897.2009.00781.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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