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Article

Hierarchical fine mapping of the cystic fibrosis modifier locus on 19q13 identifies an association with two elements near the genes CEACAM3 and CEACAM6.

Human genetics - 1 Apr 2010

Stanke Frauke, Becker Tim, Hedtfeld Silke, Tamm Stephanie, Wienker Thomas F, Tümmler Burkhard

Abstract excerpt

On 19q13, TGFB1 and the cystic fibrosis modifier 1 locus (CFM1) have been identified as modifiers of the course of the monogenic disease cystic fibrosis (CF). Recently, we have described a transmission disequilibrium at the microsatellite D19S197, localized between TGFB1 and CFM1. To map the corr...

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Share to Carcinoembryonic Antigen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

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Source

Identifiers

PMID: 20047061
DOI: 10.1007/s00439-009-0779-6

Genes

CEACAM3
CEACAM6
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20047061-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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