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Article

What controls polyspermy in mammals, the oviduct or the oocyte?

23 Dec 2009

Abstract excerpt

A block to polyspermy is required for successful fertilisation and embryo survival in mammals. A higher incidence of polyspermy is observed during in vitro fertilisation (IVF) compared with the in vivo situation in several species. Two groups of mechanisms have traditionally been proposed as contributing to the block to polyspermy in mammals: oviduct-based mechanisms, avoiding a massive arrival of spermatozoa in...

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PMID: 20039874
DOI: 10.1111/j.1469-185x.2009.00117.x

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