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Article

Use of biomarkers in the discovery of novel anti-schizophrenia drugs.

Drug discovery today - 1 Feb 2010

Mikkelsen Jens D, Thomsen Morten S, Hansen Henrik H, Lichota Jacek

Abstract excerpt

Schizophrenia is characterized by a diverse symptomatology that often includes positive, cognitive and negative symptoms. Current anti-schizophrenic drugs act at multiple receptors, but little is known about how each of these receptors contributes to their mechanisms of action. Screening of novel anti-schizophrenic drug candidates targeting single receptors will be based on biomarker assays that measure...

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Identifiers

PMID: 20036755
DOI: 10.1016/j.drudis.2009.12.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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