Article
Transferability and fine-mapping of genome-wide associated loci for adult height across human populations.
PloS one - 22 Dec 2009
Shriner Daniel, Adeyemo Adebowale, Gerry Norman P, Herbert Alan, Chen Guanjie, Doumatey Ayo, Huang Hanxia, Zhou Jie, Christman Michael F, Rotimi Charles N
Abstract excerpt
Human height is the prototypical polygenic quantitative trait. Recently, several genetic variants influencing adult height were identified, primarily in individuals of East Asian (Chinese Han or Korean) or European ancestry. Here, we examined 152 genetic variants representing 107 independent loci previously associated with adult height for transferability in a well-powered sample of 1,016 unrelated African...
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