Allelic somatic mutations may explain vascular twin nevi.

Abstract excerpt

Vascular twin nevi, i.e., telangiectatic nevus and nevus anemicus occurring together and adjacent to each other, can be explained as twin spots resulting from a somatic recombination. It is so far unclear, however, whether the postulated underlying autosomal recessive mutations are allelic. This problem can be approached by studying another cutaneous phenotype, phacomatosis pigmentovascularis. Within this...

Topics

• Alleles
• Hemangioma
• Humans
• Mutation
• Skin Neoplasms