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Article

Isolation of multipotent stem cells in human periodontal ligament using stage-specific embryonic antigen-4.

Differentiation; research in biological diversity - 1 Feb 2010

Kawanabe Noriaki, Murata Satoko, Murakami Kaoru, Ishihara Yoshihito, Hayano Satoru, Kurosaka Hiroshi, Kamioka Hiroshi, Takano-Yamamoto Teruko, Yamashiro Takashi

Abstract excerpt

The periodontal ligament (PDL) comprises adult stem cells, which are responsible for periodontal tissue regeneration. In the present study, we investigated the specific profile of the stem cells in the human PDL. Microscopic analysis demonstrated that PDL cells showed a fibroblastic appearance, forming flat and loose aggregates. PDL cells expressed embryonic stem cell-associated antigens (SSEA-1, SSEA-3, SSEA-4,...

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Cell Differentiation
Cell Lineage
Cell Proliferation
TRA gene
Lewis X Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multipotent Stem Cells

Periodontal Ligament

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PMID: 19945209
DOI: 10.1016/j.diff.2009.10.005

Genes

TRA
NANOG
SOX2

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