Article
[Characteristics of heritability and effect of selection on prevalence of diffuse-toxic goiter in population].
TSitologiia i genetika - 1 Jan 2000
Shtandel' S A, Gopkalova I V, Khaziev V V, Dubovik V N, Svetlova-Kovalenko E A
Abstract excerpt
On genealogic data about 242 Gravers disease patients, fertility parameters of 2105 healthy and 369 Grave's disease women peculiarities of genetic determination and natural selection of disease were studied. Results of the genetic analysis have revealed conformity of Grave's disease inheritance to alternative model parameters. Homozygote penetrance within the framework of this model was 78.8%,...
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