Article
A 20-year experience of electron microscopy in the diagnosis of primary ciliary dyskinesia.
The European respiratory journal - 1 May 2010
Papon J F, Coste A, Roudot-Thoraval F, Boucherat M, Roger G, Tamalet A, Vojtek A M, Amselem S, Escudier E
Abstract excerpt
Transmission electron microscopy (TEM) analysis of ciliary ultrastructure is classically used for the diagnosis of primary ciliary dyskinesia (PCD). We report our extensive experience of TEM analysis in a large series of patients in order to evaluate its feasibility and results. TEM analysis performed in 1,149 patients with suspected PCD was retrospectively reviewed. Biopsies (1,450) were obtained from nasal...
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