Article
Regulator genes affecting red cell antigens.
Transfusion medicine reviews - 1 Jan 1990
Tippett P
Abstract excerpt
Several mechanisms may be involved to explain the action of genes that regulate the expression of red cell antigens. When carbohydrate antigens are involved, lack of an enzyme in the biochemical pathway prevents formation of the precursor for the next and following steps of that path, or, alternatively, addition of an extra sugar to the immuno-dominant sugar may produce a new structure in which the expression of...
Topics
- Antigens, Surface
- Blood Group Antigens
- Erythrocytes
- Female
- Gene Expression Regulation
- Genes
- Genes, Dominant
- Genes, Regulator
- Glycosylation
- Humans
- Male
- Phenotype
