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Mechanisms of Remodelling A Question of Life (Stem Cell Production) and Death (Myocyte Apoptosis)

1 Jan 2009

Abstract excerpt

Remodeling myocytes show a typical switch between the embryonic and classical features of apoptosis and/or hypertrophy representing a signal of death (ie, apoptosis) and a signal of life (ie, hypertrophy). The adult myocyte, however, is a terminal cell; usually it is unable to reproduce and death is not genetically programmed (apoptosis), but occurs by necrosis. The reinstatement of apoptosis and development of...

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PMID: 19822975
DOI: 10.1253/circj.cj-09-0573

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