Article
ScoC regulates bacilysin production at the transcription level in Bacillus subtilis.
Journal of bacteriology - 1 Dec 2009
Inaoka Takashi, Wang Guojun, Ochi Kozo
Abstract excerpt
Bacillus subtilis mutants with high expression of the bacilysin operon ywfBCDEFG were isolated. Comparative genome sequencing analysis revealed that all of these mutants have a mutation in the scoC gene. The disruption of scoC by genetic engineering also resulted in increased expression of ywfBCDEFG. Primer extension and gel mobility shift analyses showed that the ScoC protein binds directly to the promoter...
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