Article
Functional phenotypes and gene expression profiles of peripheral blood mononuclear cells in chronic hepatitis C patients who developed non-Hodgkin's B-cell lymphoma.
Biochemical and biophysical research communications - 11 Dec 2009
Ito Masahiko, Mizoroki Fumi, Takai Kenji, Yamaguchi Kazunari, Mizuochi Toshiaki
Abstract excerpt
Epidemiological data have indicated a close relationship between chronic HCV infection and non-Hodgkin's B-cell lymphoma (B-NHL). In this study, functional phenotypes and gene expression profiles of PBMCs were analyzed in chronic hepatitis C (CHC) patients who developed B-NHL. The frequencies of effector CD8(+) T cells and cytotoxic natural killer cells increased in CHC patients with B-NHL compared to those in...
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