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Mining SNPs from DNA sequence data; computational approaches to SNP discovery and analysis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

van Oeveren Jan, Janssen Antoine

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are the most abundant form of genetic variation and are the basis for most molecular markers. Before these SNPs can be used for direct sequence-based SNP detection or in a derived SNP assay, they need to be identified. For those regions or species where no validated SNPs are available in the public databases, a good alternative is to mine them from DNA sequences. The...

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PMID: 19768587
DOI: 10.1007/978-1-60327-411-1_4

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