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Article

Cell surface expression of adhesins for fibronectin correlates with virulence in Sporothrix schenckii

30 Oct 2009

Abstract excerpt

The virulence of four Sporothrix schenckii isolates was compared in a murine model of sporotrichosis, together with the protein pattern of the yeast cell surface and the capacity to bind the extracellular matrix protein fibronectin. Virulence was determined by the mortality rate, fungal burden and histopathology. Two clinical isolates were more virulent for C57BL/6 mice, but no direct correlation was seen between...

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PMID: 19762444
DOI: 10.1099/mic.0.029439-0

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