Article
Classic virilizing congenital adrenal hyperplasia presenting late: case series from Pakistan.
JPMA. The Journal of the Pakistan Medical Association - 1 Sept 2009
Khan Aysha Habib, Aban Muniba, Rameez-ul-Hassan, Naeem-ul-Haq, Raza Jamal, Jabbar Abdul, Moatter Tariq
Abstract excerpt
Deficiency of 21 hydroxylase enzyme deficiency (21OH) activity accounts for 90% cases of congenital adrenal hyperplasia (CAH). This results in deficient cortisol, increased ACTH, adrenal hyperplasia and increased adrenal androgen secretion. There is marked virilization in genetic females which is the hallmark of this disorder. Genetic heterogeneity in 21 OHD is well recognized, and both severe and mild forms...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.