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Article

Measuring the sensitivity of single-locus "neutrality tests" using a direct perturbation approach.

Molecular biology and evolution - 1 Jan 2010

Garrigan Daniel, Lewontin Richard, Wakeley John

Abstract excerpt

A large number of statistical tests have been proposed to detect natural selection based on a sample of variation at a single genetic locus. These tests measure the deviation of the allelic frequency distribution observed within populations from the distribution expected under a set of assumptions that includes both neutral evolution and equilibrium population demography. The present study considers a new way to...

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Identifiers

PMID: 19744997
DOI: 10.1093/molbev/msp209
PMCID: PMC2794309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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