An infrequent DNA polymorphism associated with severe von Willebrand's disease.

doi:10.1111/j.1365-2141.1990.tb02619.x

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Article

An infrequent DNA polymorphism associated with severe von Willebrand's disease.

British journal of haematology - 1 May 1990

Caekebeke-Peerlinck K M, Bakker E, Briet E

Abstract excerpt

Genomic DNA of six unrelated Dutch patients with severe von Willebrand's disease (vWD) was submitted to restriction fragment length polymorphism analysis. We observed a strong association between a 36 kb allele detected by a partial complementary DNA probe (pvWF 1100) and the restriction enzyme X...

Topics

Alleles
Blotting, Southern
DNA
DNA Probes
Female
Humans
Male
Pedigree
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Restriction Mapping
von Willebrand Diseases

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