Article
p53 expression in tumor stromal fibroblasts is associated with the outcome of patients with invasive ductal carcinoma of the breast.
Cancer science - 1 Nov 2009
Hasebe Takahiro, Okada Nao, Tamura Nobuko, Houjoh Takashi, Akashi-Tanaka Sadako, Tsuda Histoshi, Shibata Tatsuhiro, Sasajima Yuko, Iwasaki Motoki, Kinoshita Takayuki
Abstract excerpt
The purpose of this study was to determine whether p53 protein expression in tumor stromal fibroblasts assessed immunohistochemically by the Allred score system is significantly associated with nodal metastasis by invasive ductal carcinoma (IDC), and significantly associated with the outcome of 1042 IDC patients according to adjuvant therapy status, UICC pTNM stage, and triple-negative IDC status, in multivariate...
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