Article
Germ-line mosaicism simulates genetic heterogeneity in Wiskott-Aldrich syndrome.
American journal of human genetics - 1 May 1990
Arveiler B, de Saint-Basile G, Fischer A, Griscelli C, Mandel J L
Abstract excerpt
The Wiskott-Aldrich syndrome (IMD2) is an X-linked recessive immunodeficiency. Initial linkage studies mapped the disease locus on the proximal short arm of the X chromosome, a localization which was further refined to the interval framed by DXS7 and DXS14. We have recently shown that a novel hypervariable locus, DXS255, is very closely linked to the disease gene and is likely to be, at present, the marker...
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