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Article

Plasma miR-208 as a Biomarker of Myocardial Injury

20 Aug 2009

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are endogenous small RNAs of 21-25 nucleotides that can pair with sites in 3' untranslated regions in mRNAs of protein-coding genes to downregulate their expression. Recently, circulating miRNAs have been reported as promising biomarkers for various pathologic conditions. We assessed the hypothesis that miRNAs may leak into the circulating blood from injured cells and thereby serve...

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Share to Cardiac Fibrosis and Remodeling
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PMID: 19696117
DOI: 10.1373/clinchem.2009.125310

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