Article
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma.
The New England journal of medicine - 3 Sept 2009
Mok Tony S, Wu Yi-Long, Thongprasert Sumitra, Yang Chih-Hsin, Chu Da-Tong, Saijo Nagahiro, Sunpaweravong Patrapim, Han Baohui, Margono Benjamin, Ichinose Yukito, Nishiwaki Yutaka, Ohe Yuichiro, Yang Jin-Ji, Chewaskulyong Busyamas, Jiang Haiyi, Duffield Emma L, Watkins Claire L, Armour Alison A, Fukuoka Masahiro
Abstract excerpt
BACKGROUND: Previous, uncontrolled studies have suggested that first-line treatment with gefitinib would be efficacious in selected patients with non-small-cell lung cancer. METHODS: In this phase 3, open-label study, we randomly assigned previously untreated patients in East Asia who had advanced pulmonary adenocarcinoma and who were nonsmokers or former light smokers to receive gefitinib (250 mg per day) (609...
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