Article
Genes of cathepsin L-like proteases in Trypanosoma rangeli isolates: markers for diagnosis, genotyping and phylogenetic relationships.
Acta tropica - 1 Dec 2009
Ortiz P A, Maia da Silva F, Cortez A P, Lima L, Campaner M, Pral E M F, Alfieri S C, Teixeira M M G
Abstract excerpt
We have sequenced genes encoding cathepsin L-like (CatL-like) cysteine proteases from isolates of Trypanosoma rangeli from humans, wild mammals and Rhodnius species of Central and South America. Phylogenetic trees of sequences encoding mature CatL-like enzymes of T. rangeli and homologous genes from other trypanosomes, Leishmania spp. and bodonids positioned sequences of T. rangeli (rangelipain) closest to T....
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