Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions.

BMC veterinary research - 7 Aug 2009

Barrey Eric, Mucher Elodie, Jeansoule Nicolas, Larcher Thibaut, Guigand Lydie, Herszberg Bérénice, Chaffaux Stéphane, Guérin Gérard, Mata Xavier, Benech Philippe, Canale Marielle, Alibert Olivier, Maltere Péguy, Gidrol Xavier

Abstract excerpt

BACKGROUND: Several cases of myopathies have been observed in the horse Norman Cob breed. Muscle histology examinations revealed that some families suffer from a polysaccharide storage myopathy (PSSM). It is assumed that a gene expression signature related to PSSM should be observed at the transc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycogen
Share to Horse Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Horses

Share to Hypoxia

Share to Inflammation

Share to Muscle, Skeletal

Share to Muscular Diseases

Share to Polysaccharides

Source

Open in PubMed Open full text

Identifiers

PMID: 19664222
DOI: 10.1186/1746-6148-5-29
PMCID: PMC2741442

Genes

GYS1
CTSS
LUM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19664222-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions.PMID 19664222Read ↗

Allele copy number and underlying pathology are associated with subclinical severity in equine type 1 polysaccharide storage myopathy (PSSM1).Semantic proximity Read ↗

A glycogen synthase 1 mutation associated with equine polysaccharide storage myopathy and exertional rhabdomyolysis occurs in a variety of UK breeds.Semantic proximity Read ↗

Glycogen synthase (GYS1) mutation causes a novel skeletal muscle glycogenosis.Semantic proximity Read ↗

A GYS1 gene mutation is highly associated with polysaccharide storage myopathy in Cob Normand draught horses.Semantic proximity Read ↗

Glycogen synthase 1 (GYS1) mutation in diverse breeds with polysaccharide storage myopathy.Semantic proximity Read ↗

Clinical characteristics and muscle glycogen concentrations in warmblood horses with polysaccharide storage myopathy.Semantic proximity Read ↗

Comparative skeletal muscle histopathologic and ultrastructural features in two forms of polysaccharide storage myopathy in horses.Semantic proximity Read ↗

Muscular microRNA expressions in healthy and myopathic horses suffering from polysaccharide storage myopathy or recurrent exertional rhabdomyolysis.Semantic proximity Read ↗

Polysaccharide storage myopathy phenotype in quarter horse-related breeds is modified by the presence of an RYR1 mutation.Semantic proximity Read ↗

A highly prevalent equine glycogen storage disease is explained by constitutive activation of a mutant glycogen synthase.Semantic proximity Read ↗

Commercial genetic testing for type 2 polysaccharide storage myopathy and myofibrillar myopathy does not correspond to a histopathological diagnosisSemantic proximity Read ↗

Prevalence of polysaccharide storage myopathy in horses with neuromuscular disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.