New insight into mechanisms of pruritus from molecular studies on familial primary localized cutaneous amyloidosis

Abstract excerpt

Macular and lichen amyloidosis are common variants of primary localized cutaneous amyloidosis (PLCA) in which clinical features of pruritus and skin scratching are associated with histological findings of deposits of amyloid staining on keratinous debris in the papillary dermis. Most cases are sporadic, but an autosomal dominant family history may be present in up to 10% of cases, consistent with a genetic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Contact Dermatitis and Allergies
• Share to Dermatology and Skin Diseases
• Share to Urticaria and Related Conditions