Article
CADISP-genetics: an International project searching for genetic risk factors of cervical artery dissections.
International journal of stroke : official journal of the International Stroke Society - 1 Jun 2009
Debette S, Metso T M, Pezzini A, Engelter S T, Leys D, Lyrer P, Metso A J, Brandt T, Kloss M, Lichy C, Hausser I, Touzé E, Markus H S, Abboud S, Caso V, Bersano A, Grau A, Altintas A, Amouyel P, Tatlisumak T, Dallongeville J, Grond-Ginsbach C
Abstract excerpt
BACKGROUND: Cervical artery dissection (CAD) is a frequent cause of ischemic stroke, and occasionally death, in young adults. Several lines of evidence suggest a genetic predisposition to CAD. However, previous genetic studies have been inconclusive mainly due to insufficient numbers of patients. Our hypothesis is that CAD is a multifactorial disease caused by yet largely unidentified genetic variants and...
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