Article
Numerical solution of the Penna model of biological aging with age-modified mutation rate.
Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Jun 2009
Magdoń-Maksymowicz M S, Maksymowicz A Z
Abstract excerpt
In this paper we present results of numerical calculation of the Penna bit-string model of biological aging, modified for the case of a -dependent mutation rate m(a), where a is the parent's age. The mutation rate m(a) is the probability per bit of an extra bad mutation introduced in offspring inherited genome. We assume that m(a) increases with age a. As compared with the reference case of the standard Penna...
Topics
- Aging
- Algorithms
- Animals
- Genetics, Population
- Humans
- Models, Genetic
- Mortality
- Mutation