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Article

Census and analysis of persistent false-negative results in serological diagnosis of human immunodeficiency virus type 1 group O infections.

Journal of clinical microbiology - 1 Sept 2009

Plantier J-C, Djemai M, Lemée V, Reggiani A, Leoz M, Burc L, Vessière A, Rousset D, Poveda J-D, Henquell C, Gautheret-Dejean A, Barin F

Abstract excerpt

Human immunodeficiency viruses (HIV) have a high level of genetic diversity. The outlier variants of HIV type 1 (HIV-1) group O are distantly related to HIV-1 group M. Their divergence has an impact on serological diagnosis, with a risk of false-negative results. In this study, we report 20 failure cases, involving patients with primary or chronic infection, in France and Cameroon between 2001 and 2008. Our...

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Identifiers

PMID: 19625478
DOI: 10.1128/JCM.00602-09
PMCID: PMC2738113

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Source receipt: pubmed, retrieved 7 Sept 2026.

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