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Article

Newly identified cytoskeletal components are associated with dynamic changes of podocyte foot processes

17 Jul 2009

Abstract excerpt

BACKGROUND: Proteinuria, one of the main manifestations of nephrotic syndrome, is an important risk factor for the progression of renal diseases. Podocyte foot processes (FPs) injury induces proteinuria in most renal diseases. The podocyte cytoskeleton plays important roles in maintaining the normal morphology of FPs. However, the underlying cytoskeletal component that initiates and regulates the dynamic changes...

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PMID: 19617259
DOI: 10.1093/ndt/gfp338

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