Article
Staphylococcus aureus clfB and spa alleles of the repeat regions are segregated into major phylogenetic lineages.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2009
Basset Patrick, Hammer Nevena Basic, Kuhn Gerrit, Vogel Valérie, Sakwinska Olga, Blanc Dominique S
Abstract excerpt
To reliably differentiate among Staphylococcus aureus isolates we recently developed the Double Locus Sequence Typing (DLST) based on the analysis of partial sequences of clfB and spa genes. This method is highly discriminatory and gives unambiguous definition of types. The highly clonal population structure of S. aureus suggests that isolates with identical clfB or spa alleles belong to the same clonal complex...
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