Article
Development and evaluation of a novel multiple-antigen ELISA for serodiagnosis of tuberculosis.
Tuberculosis (Edinburgh, Scotland) - 1 Jul 2009
Zhang Shu-Lin, Zhao Jun-Wei, Sun Zhan-Qiang, Yang En-Zhuo, Yan Ji-Huan, Zhao Qi, Zhang Guo-Long, Zhang Hong-Mei, Qi Yuan-Ming, Wang Hong-Hai, Sun Qing-Wen
Abstract excerpt
In this study, we describe the development and evaluation of a novel multiple-antigen ELISA for rapid diagnosis and screening of active tuberculosis (TB). The humoral immune responses of 136 active TB patients and 57 healthy subjects against antigens Rv3425, 38kDa and lipoarabinomannan (LAM) from Mycobacterium tuberculosis H37Rv were examined by ELISA. Three essential results were obtained. (i) Rv3425 antigen is...
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