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Article

The heritability of P300 amplitude in 18-year-olds is robust to adolescent alcohol use.

Psychophysiology - 1 Sept 2009

Perlman Greg, Johnson Wendy, Iacono William G

Abstract excerpt

P3 amplitude reduction (P3AR) is associated with adolescent alcohol use (AAU) and highly heritable, suggesting that P3AR may index a genetic predisposition (e.g., an endophenotype) for AAU. However, because P3AR and AAU covary naturally in the population, these observations are also consistent with P3AR reflecting neurotoxic effects of AAU on the developing adolescent brain. In this report, we describe the use of...

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Source

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Identifiers

PMID: 19558402
DOI: 10.1111/j.1469-8986.2009.00850.x
PMCID: PMC2892841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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