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Prevalence of the Genes Encoding Aminoglycoside-Modifying Enzymes and Methicillin Resistance Among Clinical Isolates of <i>Staphylococcus aureus</i> in Tehran, Iran

1 Jun 2009

Abstract excerpt

Aminoglycosides are potent bactericidal agents that play an important role in antistapylococcal therapy. In this study, we used a multiplex polymerase chain reaction assay to investigate the prevalence of aac(6')-Ie/aph(2''), ant(4')-Ia, and aph(3')-IIIa, the genes encoding the most clinically prevalent aminoglycoside-modifying enzymes, and simultaneous detection of the methicillin resistance gene, mecA, in...

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PMID: 19496674
DOI: 10.1089/mdr.2009.0897

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