Article
A pilot study to assess the feasibility of a multicenter cluster randomized trial for the management of asymptomatic persons with a thrombophilia.
Journal of genetic counseling - 1 Oct 2009
Wells Philip S, Louzada Martha L, Taljaard Monica, Anderson David R, Kahn Susan R, Langlois Nicole J, Rutberg Julie, Kovacs Michael J, Rodger Marc A
Abstract excerpt
There is controversy whether asymptomatic first-degree relatives (FDRs) of patients with venous thromboembolism (VTE) and thrombophilia should be screened, followed, and prescribed prophylaxis during risk periods. We recruited consecutive probands with idiopathic VTE and thrombophilia from our thrombosis clinics. Those FDRs with thrombophilia were randomized in family clusters to receive one-time verbal...
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