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Article

Small mutations detected by multiplex ligation-dependent probe amplification of the dystrophin gene.

Genetic testing and molecular biomarkers - 1 Jun 2009

Okizuka Yo, Takeshima Yasuhiro, Awano Hiroyuki, Zhang Zhujun, Yagi Mariko, Matsuo Masafumi

Abstract excerpt

Currently, multiplex ligation-dependent probe amplification (MLPA) has been recognized as the most powerful and convenient method to identify exon deletions or duplications in the dystrophin gene, the mutation of which causes Duchenne and Becker muscular dystrophies (DMD/BMD). The mutation diagnosis is easily done by assessing the amounts amplified by MLPA (loss, single, or double). However, an ambiguous amount...

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Identifiers

PMID: 19473085
DOI: 10.1089/gtmb.2009.0002

Genes

DMD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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