Article
In vitro activity of tigecycline in combination with various antimicrobials against multidrug resistant Acinetobacter baumannii.
Annals of clinical microbiology and antimicrobials - 21 May 2009
Principe Luigi, D'Arezzo Silvia, Capone Alessandro, Petrosillo Nicola, Visca Paolo
Abstract excerpt
BACKGROUND: Infections sustained by multidrug-resistant (MDR) and pan-resistant Acinetobacter baumannii have become a challenging problem in Intensive Care Units. Tigecycline provided new hope for the treatment of MDR A. baumannii infections, but isolates showing reduced susceptibility have emerged in many countries, further limiting the therapeutic options. Empirical combination therapy has become a common...
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