Article
From genes to function: the next challenge to understanding multiple sclerosis.
Nature reviews. Immunology - 1 Jun 2009
Fugger Lars, Friese Manuel A, Bell John I
Abstract excerpt
Susceptibility to multiple sclerosis is jointly determined by genetic and environmental factors, and progress has been made in defining some of these genetic associations, as well as their possible interactions with the environment. However, definitive proof for the involvement of specific genetic determinants in the disease will only come from studies that examine their functional roles in disease pathogenesis....
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