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Preliminary evidence of a genetic association between tumor necrosis factor alpha and the severity of sleep disturbance and morning fatigue.

Biological research for nursing - 1 Jul 2009

Aouizerat Bradley E, Dodd Marylin, Lee Kathryn, West Claudia, Paul Steven M, Cooper Bruce A, Wara William, Swift Patrick, Dunn Laura B, Miaskowski Christine

Abstract excerpt

Although fatigue and sleep disturbance are prevalent symptoms in oncology patients and their family caregivers, little is known about the factors that contribute to interindividual variability in symptom severity ratings as well as in their underlying biological mechanisms. In this study, we sought to determine whether a functional genetic variation in a prominent proinflammatory cytokine, tumor necrosis...

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PMID: 19419979
DOI: 10.1177/1099800409333871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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