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GeneRegionScan: a Bioconductor package for probe-level analysis of specific, small regions of the genome.

Bioinformatics (Oxford, England) - 1 Aug 2009

Folkersen Lasse, Diez Diego, Wheelock Craig E, Haeggström Jesper Z, Goto Susumu, Eriksson Per, Gabrielsen Anders

Abstract excerpt

SUMMARY: Whole-genome microarrays allow us to interrogate the entire transcriptome of a cell. Affymetrix microarrays are constructed using several probes that match to different regions of a gene and a summarization step reduces this complexity into a single value, representing the expression level of the gene or the expression level of an exon in the case of exon arrays. However, this simplification eliminates...

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Identifiers

PMID: 19398447
DOI: 10.1093/bioinformatics/btp279
PMCID: PMC2712334

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