Article
[Identification of a novel HLA allele DRB1*1462 by sequence-based typing].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2009
Cui Shuang, Shan Xiao-Yan, He Xiao-Mei, Liu Na, Wang Lin, Li Wei, Wang Li-Jun, Ni Lei, Wang Dong-Mei, Zhao Bo-Tao, Gong Zhi-Yin, Zhang Zhi-Xin
Abstract excerpt
This study was to identify a novel HLA-DRB1 allele in Chinese population by nucleotide sequence ana- lysis. The HLA typing of genes was performed by PCR-SSO and PCR-SSP, the ambiguous novel allele was identified by DNA sequence analysis. The results showed that the sequence of this new allele differed from DRB1*140101 by one nucleotide substitution at position 256 in exon 2 (G- > A), resulting in an amino acid...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.