Article
Phenotyping tea consumers by nutrikinetic analysis of polyphenolic end-metabolites.
Journal of proteome research - 1 Jul 2009
van Velzen Ewoud J J, Westerhuis Johan A, van Duynhoven John P M, van Dorsten Ferdi A, Grün Christian H, Jacobs Doris M, Duchateau Guus S M J E, Vis Daniël J, Smilde Age K
Abstract excerpt
An integration of metabolomics and pharmacokinetics (or nutrikinetics) is introduced as a concept to describe a human study population with different metabolic phenotypes following a nutritional intervention. The approach facilitates an unbiased analysis of the time-response of body fluid metabolites from crossover designed intervention trials without prior knowledge of the underlying metabolic pathways. The...
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