Article
New population and phylogenetic features of the internal variation within mitochondrial DNA macro-haplogroup R0.
PloS one - 1 Jan 2009
Alvarez-Iglesias Vanesa, Mosquera-Miguel Ana, Cerezo Maria, Quintáns Beatriz, Zarrabeitia Maria Teresa, Cuscó Ivon, Lareu Maria Victoria, García Oscar, Pérez-Jurado Luis, Carracedo Angel, Salas Antonio
Abstract excerpt
BACKGROUND: R0 embraces the most common mitochondrial DNA (mtDNA) lineage in West Eurasia, namely, haplogroup H (approximately 40%). R0 sub-lineages are badly defined in the control region and therefore, the analysis of diagnostic coding region polymorphisms is needed in order to gain resolution in population and medical studies. METHODOLOGY/PRINCIPAL FINDINGS: We sequenced the first hypervariable segment (HVS-I)...
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