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Article

Pathogenesis of leukodystrophy for Krabbe disease: molecular mechanism and clinical treatment.

Brain & development - 1 Aug 2009

Sakai Norio

Abstract excerpt

We reported the basic concept of the pathology of leukodystrophy with emphasis on Krabbe disease. First, the normal process of myelination and the pathology of demyelination will be described, emphasizing the course inducing neuro-inflammation in its progression. After classifying metabolic leukodystrophy, the features of Krabbe disease (globoid-cell leukodystrophy) are explained as well as molecular cloning and...

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Source

Identifiers

PMID: 19332366
DOI: 10.1016/j.braindev.2009.03.001

Genes

GALC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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