Article
Prevalence data on all Ghent features in a cross-sectional study of 87 adults with proven Marfan syndrome.
European journal of human genetics : EJHG - 1 Oct 2009
Rand-Hendriksen Svend, Lundby Rigmor, Tjeldhorn Lena, Andersen Kai, Offstad Jon, Semb Svein Ove, Smith Hans-Jørgen, Paus Benedicte, Geiran Odd
Abstract excerpt
The prevalence of each single feature in the Ghent criteria in patients with Marfan syndrome (MFS) is not known. To elucidate this, a cross-sectional study of 105 adults with presumed MFS was carried out. All patients were examined by the same group of investigators with standardized and complete assessment of all features in the Ghent criteria. Eighty-seven (83%) fulfilled the criteria in 56 different variants....
Topics
- Adult
- Aortic Diseases
- Cohort Studies
- Cross-Sectional Studies
- Dura Mater
- Female
- Genotype
- Humans
- Male
- Marfan Syndrome
- Middle Aged
- Mutation
- Phenotype
- Prevalence