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Article

A re-examination of proliferation and differentiation of type A spermatogonia in the adult rhesus monkey (Macaca mulatta)

12 Mar 2009

Abstract excerpt

BACKGROUND: Companion studies using an experimental non-human primate paradigm known as a testicular clamp indicated that the behavior of undifferentiated type A spermatogonia did not conform fully to earlier classical models. This issue was therefore re-examined in normal monkeys. METHODS: Adult male rhesus monkeys (n = 4) received an i.v. bolus of 5-bromo-2'-deoxyuridine (BrdU): one testis (first) was removed 3...

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PMID: 19282325
DOI: 10.1093/humrep/dep051

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